From 883928e1bb654f983817cc0df72a6d51644f0025 Mon Sep 17 00:00:00 2001 From: ygutier2 <yair.fosado@ed.ac.uk> Date: Tue, 10 Aug 2021 14:53:38 +0100 Subject: [PATCH] Update README.md --- README.md | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/README.md b/README.md index 17bfd37..9f69808 100644 --- a/README.md +++ b/README.md @@ -3,7 +3,7 @@ We model a torsionally relaxed (nicked) DNA plasmid 7.2 kbp-long as a bead-spring polymer made of 1000 beads with bead-size σ=2.5 nm=7.3 bp and connected by finitely extensible springs. The persistence length of the polymer is set to lp = 50 nm. Beads interact via a purely steric Lennard-Jones repulsion while the TopoII-bound segment is modelled as a 50 beads (L=360 bp)-long segment displaying soft interactions with the other beads thereby allowing the TopoII-bound segment to undergo strand-crossing with a small energy penalty (2 kBT). For details in the model and the system used we refer the reader to our paper: *D. Michieletto, et al.* "**Dynamic and Facilitated Binding of Topoisomerase Accelerates Topological Relaxation**". -All the simulation scripts in this repository are set to start from a N=1000 beads thermally equilibrated polymer tied in a 5~1~ torus knot. This and other configurations (3~1~ and unknot) +All the simulation scripts in this repository are set to start from a N=1000 beads thermally equilibrated polymer tied in a 5<sub>1</sub> torus knot. This and other configurations (3~1~ and unknot) The position of the TopoII-bound segment can be either: -- GitLab