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Trio whole exome batch 19285 (EdGe)

  • The urgent family is 438158.
  • We know that sample 129421 (proband from family 436427) is going to fail – there was an issue during set up for this one.
  • Family 438023 – Quad, for shared analysis between two sibs and trio analysis per sib (129760 and 129850).

Duos/singleton – for Congenica only

  • 435163 (duo)
  • 436090 (duo)
  • 436525 (singleton)

QC

  • Pedigree check ok
  • Samples with slightly low coverage:
    • 128940_435163 43X
    • 128993_429270 47X
    • 126656_429218 48X
  • Contamination check ok
  • Sample 129421 was not delivered - don't analyze family 436427, parents QC'd ok
  • Sequencing QC check ok

Additional run with remove_lcr: false

Get an idea of how many additional candidate variants are returned if LCR filtering is turned off.