Run notes for batch 19573

docs/run-notes/19573_run_notes.md

+# 19573 EdGe
+
+## Issues
+
+* 447226 - sample 131873 (father) is very low depth (6X), comes up as non-paternity for 114891 as a result but this can be ignored
+* 453955 - sample 132058 (proband) comes up as incorrect sex (annotated as female in PED file but no evidence of Y coverage)
+
+## Notes
+
+* no contamination issues
+* low depth but still usable samples
+  * 438938 - sample 131858 (proband) 33X
+  * 433285 - sample 132221 (proband) 36X
+* XYY observable in X/Y coverage
+  * 452542 - sample 131311 (proband) 
+  * 438235 - sample 131376 (father)
+* Possible amplification of a region on chr4 - increased coverage observed in QC
+  * 438371 samples 131201 (proband), 131202 (mother)
+  * 454213 samples 132222 (proband), 132223 (father)