Update Software_installation_ultra2.md

docs/Software_installation_ultra2.md

@@ -48,6 +48,8 @@ DATE=`date +%Y%m%d%H%M`
 /home/u035/project/software/bcbio/tools/bin/bcbio_nextgen.py upgrade -u skip --datatarget vep &> bcbio_install_logs/bcbio_install_datatarget_vep_${DATE}.log
 ```
 
+Q: do we even need gnomAD annotations on these? Should I be skipping VEP altogether for the alignment & variant calling pipeline?
+
 We already had gnomAD 3.0 compiled and downloaded on the ultra2 bcbio installation, so this gets copied to `/home/u035/u035/shared/software/bcbio/genomes/Hsapiens/hg38/variation`.
 
 ```